Recently, have identified RGS (regulation of G- Protein signalling proteins) proteins – bind to and modulate activity of G-proteins. (e.g. Can accelerate GTPase in a-subunit to cause form of G-protein desensitisation). RGS12 binds to consequences sequence TXV/L 9expressed in CRH receptor) and has Goloco domain (vertebrate homologue of loco protein in Drosophilia) that acts as an inhibitor od guanine nucleotide dissociation and so could impeed CRH action. Some RGS proteins can intercat with b-subunit and subsitute for g-protein g-subunit. Roles of RGS in endocrine signalling yet to be elucidated.
Does anyone actually get what he is trying to say? Absolutely no structure nor organisation.
How are we supposed to make head or tail out of it when its apparently in some funny language that uses english words. Even I don’t sound that incoherent at my bad times. How in the world to revise crap notes like this, esp when it is so hot? Argh!!!!!!!!
What’s wrong with the weather gal too? Its 29 outside and 31 in my room. How can she still insist that its 23? Maybe she has not gotten updated since last night. Whatever, the heat is getting to me…..


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